With the takeover of Crimea by masked Russian soldiers/fighters without national insignia in February/March 2014, with the Kremlin at first denying its involvement, war became ‘hybrid’ in our minds.The follow-on conflict in Eastern Ukraine, with separatism supported by neighbouring countries and the armed establishment and military securing of
Paroxysmal nocturnal hemoglobinurea Film (PNH) is a rare disorder of complement regulation due to somatic mutation of PIGA (phosphatidylinositol glycan anchor) gene.We herewith report a case who developed a symptomatic PNH long after an allogenic marrow transplant.Some reasonable arguments concerning the origin of PNH clone have been discussed.The
Abstract Background Colorectal cancer is one of the major neoplasms and a leading cause of cancer death worldwide, and new preventive strategies are needed to lower the burden of this disease.Metformin, a biguanide, which is widely used for treating diabetes mellitus, has recently been suggestive to have a suppressive effect on tumorigenesis and ca
Abstract Introduction Selection of the K103N mutation is associated with moderately reduced in vitro fitness of HIV.Strains bearing K103N in vivo tend to persist, even in the absence of additional drug pressure, as minority quasispecies, often undetectable in genotyping resistance testing assays, performed at standard conditions.Here, we report on
With urbanisation and population growth, understanding spatial interactions in cities is increasingly vital for urban management.In recent decades, spatial Pot Holders interactions could be predicted accurately with the support of large GPS data, but anonymous trajectory data lacks semantic details, limiting predictions and behaviour understanding.